Publications

Publications2020-09-07T19:36:12+00:00

Science Publications

Cutting-edge research from the Grace Science team has led to breakthroughs in our understanding of NGLY1 functions.

ACS CENTRAL SCIENCE

Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity

HUMAN MOLECULAR GENETICS

Ngly1 rats develop neurodegenerative phenotypes
and pathological abnormalities

JOURNAL OF EXPERIMENTAL MEDICINE

N-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1

CELL

Protein Sequencing Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression

Mainstream Publications

Grace Science’s innovative approach to rare disease has garnered national media attention.

NEW YORK TIMES

‘It Will Consume Your Life’: 4 Families Take On Rare Diseases

STANFORD BUSINESS

With Grace

WIRED

A Family’s Race To Cure A Daughter’s Genetic Disease

FAST COMPANY

This Father Founded A Medical Research Startup To Save His Kid’s Life

STANFORD NEWS

A Rare Disease Inspires Stanford Researchers To Find A New Way To Attack Cancer

NEW YORK TIMES

Parents of Children With Rare Diseases Find Hope in For-Profit Companies

Rare Unlocks Common

Grace Science is leveraging NGLY1 biology to treat human disease.

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