Cutting-edge research from the Grace Science team has led to breakthroughs in our understanding of NGLY1 functions.
Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity
Ngly1 rats develop neurodegenerative phenotypes
and pathological abnormalities
N-glycanase NGLY1 regulates mitochondrial homeostasis and inflammation through NRF1
Grace Science’s innovative approach to rare disease has garnered national media attention.
Rare Unlocks Common
Grace Science is leveraging NGLY1 biology to treat human disease.